The Jurassic Park film is a science fiction movie directed and produced more than two decades ago. In the film, the park is created by John Hammond and is made up of dinosaurs that have been bioengineered. Hammond invites paleontologists Dr. Allan Grant and Dr. Sattler together with Ian Malcolm, a mathematician (Spielberg par 1). He explains to them the bioengineering process of generating dinosaurs from fossilized mosquito blood by the use of polymerase chain reaction (PCR) alongside the DNA combination from frogs. He did the DNA combination to occupy the gaps of links that were missing to make the DNA complete. The creation of the dinosaurs was however aiming at generating female dinosaurs to prevent mating and breeding which according to Malcolm was not a good idea (Spielberg par 2) The Dinosaurs had undergone genetic alterations and were unable to produce lysine, an essential amino acid for vertebrates and were now dependant on the lysine supplements provided in the park.
Denis Nedry, one of the park attendants, steals the bioengineered embryos and sell it to the corporate competitors of Hammond. He is however killed by a dinosaur that spits venom before he could even sell the embryos. A virus that Nedry had introduced in the security system renders the electric fence powerless, and Tyrannosaurus Rex dinosaur gets out and attacks Malcolm, Ellie, grant and Hammond’s grandchildren Lex and Tim. Grant, Tim, and Lex come across dinosaur eggs after seeking refuge after the attack, an indication that there were breeding and mating cases in action, which was not to be the case (Spielberg par 4). The dinosaurs get out of hand and kill Arnold in his attempt to stop Nedry’s virus attack as well as Muldon, the park warden. The genetically bioengineered raptors became ferocious and aggressive but were all killed by the Tyrannosaurus Rex, creating room for Hammond and the group to escape.
In the case of using the mosquito blood, the chosen mosquito for the process ought to have a single dinosaur species as the source of food to avoid confusion. Some mosquito species have a female lifespan of a few days, and they end up laying eggs after every feeding. It, therefore, meant that a lot of mosquitoes from different species would have to be located to generate a variety of dinosaurs. The DNA sequence of the dinosaurs falls in between that of crocodiles and birds making it difficult to tell the exact species of the dinosaur. The generated dinosaurs had to contain all the chromosomes with no sequence spaces (Spielberg par 6). This forced Hammond to use the DNA of a frog to ensure compensation of the gaps in the DNA of the dinosaur. It is, however, tricky because Hammond was forced to determine which dinosaur genes are homologous with the genes of frogs. The frogs were used as a plot device to give room for some females to breed and also change sex. There was mixing of the frog DNA with that of viral, mosquito and bacterial DNA. In as much as PCR is a specific process, it is delicate and susceptible to contamination with the use of wrong primers.
Since the nucleus is responsible for breaking down the DNA in the gut of the mosquito, it would mean that the mosquitoes get well preserved after feeding. It would, however, be difficult for Hammond to do this but would be useful in explaining group contamination in the samples. There is, however, an alteration of molecules during the process of fossilization. It is impossible for DNA to thrive entirely with no gaps for an extended period (Spielberg par 8). Hammond and INGEN were able to buy an entire stock of amber, which is the best DNA preservative to come up with a maximum possible blood samples number from the ancient mosquitoes.
Spielberg, Stephen. “Jurassic Park (1993 Film) Summary”. Gradesaver.Com, 1993, https://www.gradesaver.com/jurassic-park-1993-film/study-guide/summary. Accessed 21 Mar 2019.